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Male and female GHK-Cu cohorts and saline cohorts had comparable values for escape hole attempts on the first trial, but male and female mice given intranasal GHK-Cu demonstrated fewer escape hole attempts on their final attempt to escape compared to the intranasal saline cohorts (Figure 3C)

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ThermoFisher Scientific) and gene expression analysis was performed on the StepOnePlus Real-Time PCR system software v.2.3 (ThermoFisher Scientific) using specific primer sets (Supplementary Table 2)