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The result of these cellular injuries manifests clinically as reduced fertilization rates, lower-quality embryos, and increased developmental arrest in PCOS-associated infertility (70)

Neuroscience (2017) 357:24154

It happens because saliva production naturally drops during sleep, and anything that compounds that drop makes symptoms worse: mouth breathing, dehydration, medications, sleep apnea, or underlying conditions like Sjgrens syndrome or diabetes