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Plant-based diets contain no natural B12

Future blood tests to continue to monitor B12 also help make sure a person maintains good vitamin levels even if they have a flare-up of UC symptoms

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This efficacy limitation, rather than safety concerns, halted further development

History [edit] Descriptions of deficiency effects [edit] Between 1849 and 1887, Thomas Addison described a case of pernicious anemia, William Osler and William Gardner first described a case of neuropathy, Hayem described large red cells in the peripheral blood in this condition, which he called "giant blood corpuscles" (now called macrocytes), Paul Ehrlich identified megaloblasts in the bone marrow, and Ludwig Lichtheim described a case of myelopathy