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doi: 10.1016/j.cvsm.2004.10.002

Lifestyle interventions (including diet, exercise and behavioural changes) are the cornerstone of obesity management with diverse benefits, but even the most intensive lifestyle interventions result in up to 10% mean weight loss (WL) and weight maintenance remains a challenge, as 80% of WL is expected to be regained over the next 5 years [4, 5]

Progressive telomere shortening has been consistently associated with cellular senescence and replicative limits in a wide range of in vitro and experimental studies

The chronic morbidity burden of COVID-19 extends much wider, with up to 10% of individuals across a spectrum of initial disease severity estimated to suffer from long COVID, a durable multisystemic condition with multiple adverse outcomes, such as, myalgia, fatigue, and neurocognitive dysfunction [7]

Lowering the level of stress-related hormones and cytokines could help animals reduce inflammation and increase the chance of surviving the injury