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The activation of GRB2 results in signal transduction via the activation of the guanine nucleotide exchange factor, SOS (son of sevenless encoded by the SOS1 gene) which in turn activates the monomeric G-protein, RAS

It also stimulates the secretion of growth hormone without increasing cortisol or ghrelin levels

Trends in Neuroscience 30, 37-45CrossRefGoogle ScholarPubMed Patenaude, A., Murthy, M.R

Specific exercises that strengthen the intrinsic foot muscles, stretch the calf and Achilles complex, and improve ankle mobility support the healing tissue