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It has been reported that selenium-rich yeast could reverse the levels of cytokines IFN-, IL-10, IL-6, and IL-1 by inhibiting TLR4/MYD88 signaling and prolonging NF-B signaling, to antagonize the oxidative stress and inflammation induced by OTA exposure, and reduce intestinal pathological damage [110]

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The modifications are reversible and are achieved with the aid of related enzymes