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In some embodiments, the amount of thermoreversible polymer (e.g., pluronic F127) in any formulation described herein is about 25% of the total weight of the formulation

In some instances, a hyaluronidase described herein is a PEGylated hyaluronidase (e.g., PEGPH20 (Halozyme))

The following principles apply: Do not pour the solution down the sink or toilet pharmaceutical compounds can pass through water treatment systems and enter the environment, where they may affect aquatic organisms and ecosystems Do not place liquid solutions directly into household waste this risks accidental exposure to others, including children and waste handlers Return unused medicines to a community pharmacy UK pharmacies are legally required to accept unwanted medicines for safe disposal under the NHS medicines take-back scheme

The compound has been characterized across thousands of peer-reviewed publications examining its role in cellular biology