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The placebo-subtracted weight loss was 4.5% for TE 0.25 mg, 9.2% for TE 0.5 mg, and 10.6% for TE 1.0 mg over 24 weeks

FDA.gov (2023) 10

Multiple studies have reported that Epithalon administration can extend both mean and maximum lifespan by 10-25% or more compared to control animals - effects approaching those seen with caloric restriction

12 Preclinical data also have shown that it rapidly increases mGlu2 receptor expression via histone acetylation, leading to sustained antidepressant-like effects

() Different sources discuss how NAD intravenous therapy is not one-size-fits-all and may trigger elevated hs-CRP markers of inflammation