weight loss surgery vs glp-1 Bariatric Study: 93.4% of Bariatric Patients Would Do the Surgery Again Metabolic surgery and GLP-1 agonists

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In contrast to the results in rodents, in vivo animal studies with cynomologus monkeys did not show any liraglutide-induced calcitonin release or any effect on relative C-cell fraction in the thyroid gland after 87 weeks at doses up to 60-fold higher than the highest dose recommended in humans [169]

While perfect adherence leads to higher premium costs due to sustained drug use, even short-term GLP-1 use incurs high pharmacy spend