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Conversely, Htr2a in mice is upregulated in UUO (LogFC = 3,26 [GSE87212]), while Htr3a (logFC = 2,32), Htr3b (logFC = 1,11) and Htr4 (logFC = 1,07) are downregulated in the murine model of UUO (GSE38117) and Htr2c is downregulated in the rat model of AKI induced by cisplatin (logFC = 1,31 [GSE37133])

doi: 10.1016/j.cmet.2018.03.001 40 DruckerDJ

Rubino et al., 2022), GLP-1 receptor agonists have been widely used in clinical practice

Melasma Melasma is a situation wherein facial skin gets pigmented especially on the nose, cheeks, upper lip, forehead, and all the sun-exposed areas of the body

GLP-1 medications are suitable for people with a body mass index (BMI) of 30 or higher (classified as obesity)