The injection itself is a small step, but it should be viewed as part of a much larger, ongoing commitment to your health
Hepatocyte cultures characterise effects on glucose output (where glucagon signalling raises and incretin signalling lowers), lipogenic gene expression, mitochondrial function, and lipid oxidation pathway activation
50100 mg once daily subcutaneously, starting low and titrating up to tolerance (flushing or GI upset) across an 812 week course
Comparatively, when these increases are quantified against a placebo baseline of 1.31 mIU/l or 0.4 ng/ml, there seems to be an enhancement that might exceed 60 times the baseline levels
Direct evidence for the effect of glucagon on lean mass is seen from clinical situations of glucagon excess, in the glucagonoma syndrome (89)