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Working Mechanism To elaborate on the mechanism, DSIP is studied because it plays a role in helping the brain shift into a deep rest state.DSIP might help control those delta wave signals that show up during slow-wave sleep by having an impact on the brains internal clock and stress pathways

Furthermore, anticholinergic medications, such as trihexyphenidyl, are used also in PD management but struggle to effectively cross the BBB and often exhibit non-specific binding, leading to undesirable peripheral effects such as dry mouth and cognitive impairment, particularly in elderly patients

Deng et al., 2021