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Patients with kidney disease, history of kidney stones, or metabolic disorders require especially careful monitoring

GLP-1 binds to receptors of pancreatic beta cells that increase insulin sensitivitywhich can increase glucose uptake and lower blood sugar levels

Clinical trials have demonstrated substantial reductions in hemoglobin A1c levels (up to 2.5% reduction at the highest doses) and body weight (up to 20% reduction in patients with obesity without diabetes in the SURMOUNT-1 trial)

This table is provided for informational comparison only and is not a substitute for guidance from a licensed medical provider