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Minimal decreases in plasma aldosterone were observed after administration of valsartan

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The hippocampus shows reduced functional connectivity bilaterally to widespread regions, including the fusiform gyrus, frontal gyrus, temporal gyrus, anterior and posterior cingulate gyri, medial frontal gyrus, precuneus, and inferior parietal lobule, compared to healthy controls [105]

Similarly to the loss of plasminogen, the loss of enzymatic activity of plasmin had similar findings of reduced fibrin endocytosis by leukocytes, further demonstrating the need for plasmin cleavage of fibrin prior to cellular uptake