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However, the expression of GPX3 is inhibited by promoter hypermethylation, resulting in the loss of cellular antioxidant capacity

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Labwork at that time was notable for an elevated uric acid of 10.6mg/dl (reference range: 3.5 - 8.5 mg/dl.) Out of concern for TLS precipitating hyperuricemia in the setting of a high-grade tumor in addition to starting a new chemotherapy regimen, the patient was additionally given 10mg of rasburicase and started on 300mg of allopurinol daily

These nutrients are known as cell-nutrients or precursors

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