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Many people begin semaglutide therapy without understanding how their lifestyle, eating habits, and pre-treatment choices affect the medications effectiveness and their ability to tolerate it comfortably

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The fastest approaches include: reducing dietary histamine intake immediately (avoid aged, fermented, and leftover foods), taking vitamin C, which research shows can support healthy blood histamine levels by up to 38% 26 , using a HEPA air purifier to reduce environmental triggers, and nasal saline irrigation to physically remove irritants