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For people on vegetarian or vegan diets, up to 90% have a vitamin B12 deficiency: even those who take extra vitamins

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130 SIRT1 deacetylates NF-B, inhibiting pro-inflammatory cytokines (IL-6, TNF-) while promoting anti-inflammatory cytokines (IL-10), 35 limiting Th17 and Tc activation and supporting overall immune balance

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Methods Plant materials and growth condition hairpin RNA-52 (hr-52) was obtained from the rolling circle amplification-mediated hairpin RNA (RMHR)-based Arabidopsis library in our previous study 19,20