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This muscle-sparing effect distinguishes it from many other fat loss approaches including some GLP-1 medications and severe caloric restriction

These extremely rare side effects include: Reactive thrombocytosis during the first week of use in megaloblastic anaemia Hypersensitivity reactions including: rash, itching, exanthema, antibodies to HYDR0XOCOBALAMIN-transcobalamin II Anaphylaxis Hypokalaemia Headache, paraesthesia, tremor Irregular heartbeat (arrhythmias secondary to hypokalaemia) Nausea Vomiting Diarrhoea Fever, chills, hot flushes, dizziness, malaise, pain and / or swelling at the injection site Acne Abnormal colouration of the urine (chromaturia) B12 injections work quickly

Though it follows a similar mechanism as GHK-Cu by signaling copper, its skin-specific benefits remain an area where additional research is developing

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Intestinal virome changes precede autoimmunity in type I diabetes-susceptible children