exendin 4 in tirzepatide GLP-1 receptor agonists got their start an unlikely place: the mouth of a lizard. A peptide discovered in Gila monster saliva, called exendin-4, was found to mimic the action of GLP-1 is exendin-4 in tirzepatide A

These findings are alarming given the widespread use of these drugs in elderly and vulnerable populations, underscoring the need for regular cognitive screening during long-term treatment

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Your healthcare team will prescribe the appropriate medication and dose based on your individual needs, kidney function, and treatment goals

doi: 10.1016/j.chembiol.2016.11.013 121 GaoXLeeKReidMASandersonSMQiuCLiSet al