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Further lipidomic profiling revealed a dramatic decrease in TGs levels in 786-O cells and a more moderate impact in Caki-1 cells expressing Cr GPDH compared to the LUC control ( Figure 7g-h , Supplementary Figure S6 , Supplementary Figure S7 ), suggesting that Cr GPDH actively clears Gro3P in kidney cancer cells, thereby inhibiting associated lipogenesis ( Figure 8a-b )

a Calculated values from reported data