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Available from: Huang K, Guo R, Luo H, Liu H, Chen D, Deng T, et al

NLRs-Inflammasome Pathway: DAMP-mediated NLRP3 Inflammasome Activation, Pyroptosis, and IL-1 Release Activated NLRs manifest diverse functionalities, which can be comprehensively classified into four primary functions: inflammasome formation, signal transduction, transcriptional activation, and autophagy

Experimental work has focused on receptor pharmacology, cyclic AMP linked signaling, food intake and energy expenditure pathways, hepatic lipid handling, inflammatory markers, and cross-tissue metabolic communication in animal and biochemical models

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