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Typical 12-month results include 10 to 15% body weight loss (20 to 35 pounds for a 200-pound person), 2 to 4 inch waist circumference reduction, noticeable improvement in body composition especially with exercise, and significant improvement in metabolic markers if they were elevated

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Massive mitochondrial degeneration in motor neurons triggers the onset of amyotrophic lateral sclerosis in mice expressing a mutant SOD1

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