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A primary clinical concern that needs to be addressed is the relationship between vitamin B deficiency and the development of depression, anxiety, and other neurological complications

[DOI] [PubMed] [Google Scholar] 58

Unlike native IGF-1, which requires frequent administration due to its short half-life and extensive IGFBP binding, IGF-1 LR3's enhanced stability and bioavailability make it a more practical candidate for investigating growth factor-mediated tissue regeneration and metabolic regulation