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In addition to GLP-1, it also mimics GIP (glucose-dependent insulinotropic polypeptide), another hormone involved in appetite and metabolism

Polyphenols such as resveratrol, fisetin, quercetin and curcumin have been shown to modulate SIRT1 signalling in cells, animals and a limited number of humans, resulting in improvements to markers of oxidative stress, metabolism and neuroprotection [117,118,119,120]

The dosing of Ipamorelin can vary depending on what the goal is, but standard longevity benefits would require a dose between 100mcg-200mcg daily in the evenings

doi: 10.7554/eLife.19375 75 MeniniSIacobiniCde LatouliereLManniIVitaleMPilozziEet al

It may be formulated in different strengths or delivery methods