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Research protocols combining GHRPs with IGF1 LR3 often use the GHRP multiple times daily (often 2-3 times) to provide pulsatile GH rise, while IGF1 LR3 is gave once daily for sustained IGF-1 receptor start

For fatigue, the centenarian trial (PMID 18065594) dosed 2 g/day over weeks before reporting reduced physical and mental fatigue the improvement was a treatment-period outcome, not a first-dose one

2013 Dec;23(12):1167-74.

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