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Even at doses far exceeding the standard 10 mcg/kg range (scaled to human-equivalent doses of roughly 200-800 mcg/day for a 70-kg adult), researchers have not observed pathological angiogenesis, tumorigenic signaling, or behavioral toxicity 1

Therefore, we hypothesized that tirazepatide dual glucagon-like peptide-1 and glucose-dependent insulinotropic polypeptide (GIP) receptor agonists might effectively manage Covid-19-induced hyperglycemia in diabetic and non-diabetic patients

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Disturbance of insulin signaling in diabetic patients might lead to the abnormal expression of Syn, damage to mitochondrial function, increase in mitochondrial oxidative stress, and down-regulation of the PI3K/AKT pathway, which in turn could promote the occurrence and development of PD (62)