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They work with the body rather than against it

Potency loss accelerates rapidly, and contamination risk increases

The animals were treated daily during five weeks with L-NAME (10 mg/kg b.w.), L-arginine (100 mg/kg b.w.), NaBPC157 (10 g/kg b.w.) and their combinations (L-NAME + NaBPC157, L-NAME + L-arginine) intraperitoneally

Overdose risks GLP-1 agonist overdose primarily causes severe gastrointestinal effects