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Correlation analysis To elucidate the potential mechanisms by which FGJ ameliorates type II diabetes, a comprehensive correlation analysis was performed, integrating data on juice composition, glycemic indices, lipid metabolism, oxidative stress markers, gut microbiota, and SCFAs (Fig

The increased expression of numerous cell adhesion molecules accelerates the adherence to the endothelium of pro-inflammatory leukocytes which in turn contributes to the development of atherosclerosis

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Empagliflozin did not increase the incidence of tumors in female rats dosed at 100, 300, or 700 mg/kg/day (up to 72 times the exposure from the maximum clinical dose of 25 mg)