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doi: 10.1016/j.prp.2016.02.001 166 UminoHHasegawaKMinakuchiHMuraokaHKawaguchiTKandaTet al

More aggressive approaches might use three cycles annually, though research supporting increased frequency remains sparse

Glucagon-like peptide-1 (GLP-1)-based therapies, such as semaglutide and tirzepatide, have transformed obesity management, producing weight loss that narrows the gap with metabolic surgery at the same time as reducing the risk of obesity-related complications [2]