We gathered GWAS summary-level data for 12 common types of psychiatric disorder, including schizophrenia, anxiety disorders, bipolar disorder, bulimia nervosa, PTSD, autism, OCD, anorexia nervosa, broad depression, MDD, and suicide or other intentional self-harm, from large-scale consortia
Risks may include joint pain, insulin resistance in some contexts, edema, carpal tunneltype symptoms, and potential tumor promotion in those with existing malignancies, which is why medical screening is important
However, for those who take an SGLT2 inhibitor and have frequent or bothersome yeast infections, consulting with a healthcare provider about different treatment options, such as metformin, may be a good idea
It was produced primarily in enteroendocrine L-cells and released together with GLP-1 in response to food intake
Supplementary material The Supplementary Material for this article can be found online at: Abbreviations AgRP, agouti-related protein