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Moreover, GLP-1 has been found to improve glycemic control and reduce the risk of developing obesity-related comorbidities such as type 2 diabetes and cardiovascular diseases

Packer M (2018) Derangements in adrenergic-adipokine signalling establish a neurohormonal basis for obesity-related heart failure with a preserved ejection fraction

This warning was grounded on a wide number of studies reviewed in (Micallef et al., 2020b) including a recent report of the French Pharmacovigilance Network conducted in 2019 ( more topical than ever (Micallef et al., 2020b)

One notable detail: the average age of ZT-002 trial participants is as low as 27 years old, yet their average weight is as high as 107 kg

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