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NCT02607865 (PIONEER 3
In 2023, the EMA's Pharmacovigilance Risk Assessment Committee (PRAC) reviewed reports of thyroid cancer and pancreatitis associated with GLP-1 receptor agonists but concluded there was no causal link for thyroid cancer and did not recommend changes to prescribing guidance based on pancreatic cancer concerns
Notably, the gastric emptying effects often diminish over time with continued therapy, which may help reduce some digestive symptoms
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