However, the most important advantage is the very safe profile of BPC (the lethal dose (LD1) could be not achieved) (Seiwerth et al., 2018), emphasized in terms of its physiological role (assessed using in situ hybridization and immunostaining for BPC 157 in the human gastrointestinal mucosa, lung bronchial epithelium, the epidermal layer of the skin, and kidney glomeruli) (Seiwerth et al., 2018)
Within weeks, people in the UK will be able to pop a glucagon-like peptide-1 (GLP-1) tablet for the first time after the government's Medicines and Healthcare products Regulatory Agency announced the much-anticipated approval of an oral version of semaglutide, the blockbuster drug better known under the brand names Wegovy and Ozempic
The appetite suppression from GLP-1 tends to quiet general hunger more effectively than it quiets specific food-seeking behaviour, at least in the early weeks
In steroidogenic tissues, such as the placenta, ovaries, testes, and adrenal cortex, it is used to hydroxylate intermediates in the conversion of cholesterol to steroid hormones, a process that makes these hydrophobic compounds more water soluble
Whether that advantage holds in broader populations, across longer treatment periods, and with varying compliance patterns remains an open question
