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Wu AB, Feng J, Yu, et al

Because of this metabolic integration, any disruption in riboflavin uptake, conversion, or mitochondrial delivery can compromise neuronal survival and glial homeostasis ( Figure 2 4.2 Regulation of oxidative stress and antioxidant systems The central nervous systemcharacterized by high oxygen consumption, intense metabolic activity, and rich lipid contentis highly susceptible to oxidative damage

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While encouraging, this studys retrospective design, lack of placebo control, small sample size, and subjective outcome reporting limit its interpretability

(2008) Etiology of fibromyalgia: The possible role of infection and vaccination