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The Science of Safety: Adverse Effects of GLP-1 Receptor Agonists as Glucose-Lowering and Obesity Medications

Clinical evaluation of melasma At the end of treatment period, hemi-MASI score was not significantly decreased on both right side (Glutathione gel treated side) ( P value = 0.1), and left side (Placebo treated side) ( P value = 0.3), with no significant difference between them ( P value=0.2) (Table 2)

The proposed exclusion of semaglutide, tirzepatide, and liraglutide from the 503B bulks list reinforces a key prioritypatient safety and evidence-based clinical necessity must remain central to formulation decisions

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doi: 10.1016/S0140-6736(10)60826-4 72 CarlsonAKRawleRAWallaceCWAdamsEGreenwoodMCBothnerBet al