cagrilintide fibrils is an amylin analogue that helps regulate appetite. In a randomized trial of over 3400 patients who were overweight or obese and had ≥1 weight-related complication, individuals assigned to a combination New in the August 14,

Metabolic regulation

Gene expression analysis of human induced pluripotent stem cell-derived neurons carrying copy number variants of chromosome 15q11-q13.1

B12 malabsorption can stem from inflammatory bowel disease, celiac disease, gastritis, pancreatic insufficiency, gastrectomy, gastric bypass surgery, or antibodies to IF

doi:10.1016/j.fertnstert.2016.12.018

eligibility typically requires a BMI of 35 kg/m or above (or 30 kg/m or above in certain ethnic groups), though thresholds vary by ICB Bariatric surgery referral for eligible patients, typically those with a BMI of 40 kg/m or above, or 35 kg/m or above with significant obesity-related comorbidities, in line with NICE guideline CG189 Structured diabetes prevention programmes for those at risk of type 2 diabetes These pathways offer genuine, monitored, and legally sanctioned routes to improved metabolic health