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Gauthier E, Milagro FI, Navas-Carretero S (2024) Effect of low-and non-calorie sweeteners on the gut microbiota: a review of clinical trials and cross-sectional studies

AC could restore PPAR levels, inhibit the activation of -catenin signaling, and reduce the apoptosis of AGEs-treated cells

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Through this activity, this compound may directly inhibit the metal ion-catalyzed oxidation of LDL particles, preventing the formation of pro-inflammatory oxidized phospholipids and lipid hydroperoxides that trigger endothelial activation and promote macrophage foam cell formation [2] [5]