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Anesthesia was initially induced with 2.0% isoflurane and maintained with 1.6% isoflurane during MRI

These biochemical adaptations result in a metabolic reprogramming that promotes lactate production and accumulation, thereby reinforcing the hypoxic cellular response

Flannagan KS, Mumford SL, Sjaarda LA, et al

Oral glutathione has poor bioavailability because stomach acid and gut enzymes break the molecule apart before it reaches the bloodstream

The key to advancing the field of copper-targeted therapy lies in the systematic coupling of innovative spatially precise delivery technologies with a dynamic multi-level biomarker framework