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J Lipid Res 52:16931701 Xu C, Bai B, Fan P et al (2013) Selective overexpression of human SIRT1 in adipose tissue enhances energy homeostasis and prevents the deterioration of insulin sensitivity with ageing in mice

Biological nanomedicines have emerged as a promising approach for combating CRC, offering advantages such as improved drug diffusion efficiency, ROS release, targeted therapy, and reduced drug resistance [165, 166]

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Similarly, carnitine/acetyl-L-carnitine has been used in treatment of degenerative neuronal function in older Down's Syndrome patients since upon autopsy it was revealed that almost 100% of these patients over 40 years of age had symptoms of dementia [117]