Overall, the most bothersome or severe symptoms reported by the patients (Figure 1) were decreased sexual interest (24%), fatigue (14%), insomnia (11%), pain during vaginal sex (10%), and general pain (10%)
Mild appetite suppression is noticeable but not overwhelming
The bottom line The Wegovy pill is the first oral GLP-1 weight-loss tablet you can actually get in the UK, and it edges Foundayo on average trial weight loss (around 13.6% vs 11.2%)
Patients should intentionally hydrate , aiming for adequate daily fluid intake consistent with national hydration guidelines , adjusted for body size and activity. Key point: Fiber without adequate fluid intake can worsen constipation by increasing stool bulk without improving passage
Before starting GLP-1 therapy Get comprehensive baseline blood work including ferritin, vitamin D, zinc, B12, thyroid panel (TSH, free T3, free T4), and a complete blood count