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Recent results using various cell types confirmed the stochastic and transient formation of superoxide radicals, termed mitochondrial flash from either a single or restricted clusters of interconnected mitochondria (O-Uchi et al

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Animal Model Evidence The systemic evidence base is entirely preclinical: Pulmonary fibrosis (mouse model): Intraperitoneal GHK-Cu at 0.2-20 micrograms/g/day protected against bleomycin-induced lung fibrosis by inhibiting TGF-beta1/Smad signaling and reducing oxidative stress (PMID 31809714)

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