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Temperature: Store refrigerated at 28 C (3646 F) for short-term use Long-Term Storage: Freeze at 20 C or lower for extended stability Light Protection: Keep protected from direct light Moisture Protection: Store in tightly sealed, dry vials Shelf Life: Typically 1224 months under proper storage conditions Diluent: Sterile water or appropriate buffer Temperature: Store refrigerated at 28 C Use Period: Recommended within 714 days after reconstitution Handling: Gently swirl to dissolve
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FDA The end of the shortage precipitated immediate legal action
In the SURMOUNT-4 trial published in the New England Journal of Medicine, participants who switched from tirzepatide to placebo regained approximately two-thirds of their lost weight over the subsequent 52 weeks, while those continuing treatment maintained their weight loss and achieved additional reductions
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