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The US National Kidney Foundation did not recommend routine administration of L-carnitine to subjects undergoing dialysis yet encouraged the development of trials in patients with select symptoms that do not respond to standard therapy, i.e., persistent muscle cramps or hypotension during dialysis, severe fatigue, skeletal muscle weakness or myopathy, cardiomyopathy, and anemia requiring large doses of erythropoietin (74, 75)
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At 24 h post-transfection, the cells were treated with AFB 1 for 24 h and then AFBO-GSH was extracted and quantified, which showed a significant increase in the production of AFBO-GSH in the AFB 1 -treated group (Fig