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479 Oxidative stress and ROS signaling associated with iron overload may mediate important factors in cardiac hypertrophy and heart failure

Pathogenesis of IPF Genetic and Environmental Factors IPF is driven by a combination of genetic susceptibility and environmental exposures

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In addition to HSCs, in an injured liver, hepatocytes and bile duct cells can also transform into fibroblasts via the process of epithelialmesenchymal transition (EMT), and excessive extracellular matrix (ECM) deposition by fibroblasts contributes to liver fibrosis