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Underlying Conditions: History of diabetes (a common cause of gastroparesis), past surgeries (especially gastric or esophageal), viral illnesses, and other chronic diseases

They may suggest temporarily slowing the titration schedule, pausing dose escalation, or reverting to a previously tolerated dose to allow your digestive system more time to adapt

Many patients find that maintaining the behavioral changes adopted during semaglutide treatmentportion control awareness, mindful eating, regular movementeases the adjustment when the medication is no longer active

This suggests that GLP-1 could send anticipatory signals of inhibited hunger via DMH GLP-1R neurons

Dordrecht: Springer Netherlands