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Thats why these medications didnt originally start out as weight loss drugs, they were diabetes medications first

This is manageable, but its easier to manage if youre expecting it

One possible interpretation could be that GLP-1 promotes cardiac performance to increase BP and HR inducing pressure natriuresis

Conversely, individuals with obesity show increased oxygen consumption in the insula, operculum, bilateral precuneus, and posterior cingulate cortex, along with the ventral putamen and Rolandic operculum, but decreased oxygen uptake in the lower caudatepatterns associated with increased impulsivity towards food stimuli (128130)

E., Pavo, I., et al (2021)