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Conditions associated with GSH depletion are far and wide: neurodegenerative, pulmonary, immune, cardiovascular, age-related, liver disease and more

Ketogenic diet promotes tumor ferroptosis but induces relative corticosterone deficiency that accelerates cachexia

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The review further distinguishes between established outcome benefits (CVD, CKD, and OSA) and conditions still under investigation (neurodegeneration, arthritis, and some liver endpoints)