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About the GEMINI-1 Clinical Trial The GEMINI-1 clinical trial was a multi-center, randomized, double-blind, placebo-controlled Phase 3 clinical study (NCT06396429) conducted by Hengrui in China to evaluate the efficacy and safety of HRS9531 injection in adults (18 years of age) with obesity (BMI 28 kg/m 2 ) or overweight (BMI 24 kg/m 2 ) and at least one weight-related comorbidity without diabetes

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Document each dose, injection site, and timing to maintain consistency

Clinical trial data from the STEP program documented hair-related adverse events, though at rates not dramatically different from placebo when controlled for weight loss magnitude

doi: 10.1038/302716a0 22 MojsovSHeinrichGWilsonIBRavazzolaMOrciLHabenerJF