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Methods 12 , 244250 (2015)

When transported into the mitochondria, the glycolytic end-product pyruvate is decarboxylated to produce acetyl-CoA by PDH complex, which reduces NAD + to NADH simultaneously

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On the other hand, similar intervention in combination with controlled hyperinsulinemia (~ 150mIU/L) elevates TC in skeletal muscle by ~ 15% [24, 25]

Inhibition of long non-coding RNA ROR reverses resistance to Tamoxifen by inducing autophagy in breast cancer