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Key concerns include hypoglycaemia (especially with insulin or sulfonylureas), gastrointestinal symptoms (nausea, vomiting, diarrhoea), diabetic ketoacidosis, dehydration, genital or urinary infections, pancreatitis, and gallbladder disease

More importantly, the reperfusion or restoration of blood flow after ischemia can also induce the increase of ROS and lipid peroxidation, leading to tissue neuronal damage and worsening of the inflammatory response

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Les symptmes qui peuvent indiquer une carence sont plutt non spcifiques et peuvent inclure une diminution des performances et une fatigue rapide, des troubles de la concentration, des dpts de graisse dans les tissus et une augmentation du cholestrol dans le sang ainsi quune augmentation de la sensibilit aux infections

Glutamine was effective at physiological concentrations (EC 50 ~0.5mM)